Curriculum Vitae

Chris Slootweg was born in Haarlem (The Netherlands) in 1978 and received his undergraduate education from Vrije Universiteit Amsterdam in 2001, with research stays at the University of Amsterdam (Prof. Piet van Leeuwen) and University of Sussex (Prof. Michael Lappert). After earning his PhD in 2005 under the supervision of Prof. Koop Lammertsma, he pursued postdoctoral studies at the ETH Zürich with Peter Chen. He started his independent scientific career in 2006 at Vrije Universiteit Amsterdam. He was promoted to Associate Professor in 2014 and moved to the University of Amsterdam in 2016. Since September 2024, he has been a full professor of circular chemistry. The mission of his laboratory is to educate students at the intersection of fundamental physical organic chemistry, main-group chemistry, and circular chemistry. Chris is co-founder and scientific advisor of SusPhos BV, a pioneering company focused on upcycling phosphate-rich waste streams to generate high-quality alternatives to replace current fossil-sourced products.

Research focus

I combine state-of-the-art synthetic chemistry, mechanistic design and computational chemistry to enable the discovery of novel sustainable chemistry by developing novel functional molecules with unique properties based on renewable resources. I coined circular chemistry (Nature Chem.) and educate students at the intersection of fundamental physical (in)organic chemistry and advanced main-group chemistry. My laboratory is recognized for studying single-electron processes in main-group (photo)chemistry to promote the homolytic bond activation and subsequent functionalisation of challenging small molecules.

Research agenda

I aim to answer how can we most effectively use our resources to improve global sustainability? Therefore, I develop novel circular technologies that use chemistry as an enabling tool to target the conservation of critical raw materials as well as contribute to solving pressing waste problems. My unique approach to chemistry combines design, synthesis and mechanistic understanding with the environmental fate and impact of current products targeting safe by design (no persistent, bio­accumulative, and toxic compounds) and design for re­use, recovery and recycling.

My motivation is to contribute to solving societal and environmental challenges, like those articulated in the UN Sustainable Development Goals to ensure sustainable consumption and production patterns, and the Dutch National Research Agenda on circular economy and resource efficiency. Based on my concept of circular chemistry, I develop practical examples to replace today’s linear ‘take–make–dispose’ approach with circular processes. I apply life cycle thinking and circularity to reinvent chemistry by developing novel chemical products and redox processes that use waste as a resource, in particular focussing on the sustainable use of phosphorus, boron and hydrogen. This is in order to optimise resource efficiency across chemical value chains and enable a closed-loop, waste-free environment. I enjoy very much the integrative approach of transferring known knowledge (education) and creating new findings by conducting novel and original research.

Selected grants and awards

• NWO VICI grant Enabling the Sustainable Use of Phosphorus through Novel Redox Cycling Processes
• H2Fuel R&D programme Development of Metal Borohydrides as Circular Hydrogen Carriers
• NWO ENW Stairway to Impact Award 2020
• NWO Gouden KIEM award for best chemical start-up of the year 2019: SusPhos BV
• Amsterdam Science & Innovation Award (natural sciences): Circular phosphate economy: Pioneers in closing the phosphorus cycle
• Thieme Chemistry Journals Award winner 2019
• Alexander von Humboldt Research Fellowship for Experienced Researchers
• NWO VIDI grant Can main-group elements do the job of transition metals?

Some other academic activities

• Editor-in-Chief of Sustainability & Circularity NOW
• Editorial Advisory Board member ChemistryEurope
• Director Demonstrator Lab Science Park
• Education Director of the bachelor programme Science, Technology & Innovation

Physical Organic Chemistry and Circular Chemistry

We combine state-of-the-art synthetic chemistry, mechanistic design and computational chemistry to enable the discovery of novel sustainable chemistry by developing novel functional molecules with unique properties based on renewable resources. In particular, we are interested in studying single-electron processes in main-group (photo)chemistry to promote the homolytic bond activation and subsequent functionalisation of challenging small molecules.

In general, we develop novel circular technologies that use chemistry as an enabling tool to target the conservation of critical raw materials as well as contribute to solving pressing waste problems. This unique approach to chemistry combines design, synthesis and mechanistic understanding with the environmental fate and impact of current products targeting safe by design (no persistent, bio­accumulative, and toxic compounds) and design for re­use, recovery and recycling.

The Hydrogen Economy

Hydrogen gas is a crucial energy carrier in the renewable energy transition, as it has a high energy capacity of 122 MJ/kg. Nonetheless, it has a low density and thus a low volumetric energy capacity; at room temperature, 1 kg of H₂ occupies a volume of 11 m³. Consequently, the storage of H₂ is a key aspect of its large-scale application as a zero-emission energy carrier.

Interestingly, NaBH₄ can act as a solid storage medium, releasing four equivalents of H₂ upon its hydrolysis with >99% efficiency. A longtime challenge of the use of NaBH₄ though is the formation of sodium metaborate, NaBO₂, as so-called ‘spent fuel’. Yet if NaBO₂ can be reused in the process, NaBH₄ becomes a circular hydrogen storage material. Recently, we have developed a circular, waste-free method to regenerate NaBH₄ through the electrochemical recycling of the NaBO₂ spent fuel. This discovery lays the groundwork for the large-scale application of sodium borohydride as a sustainable hydrogen storage medium, and thus opens up exciting opportunities for importing hydrogen on a large, commercial scale.

Phosphorus Chemistry

Phosphorus is essential for life on Earth and plays a prominent role in modern science and technology, where organophosphorus compounds are of immense importance for their wide-ranging applications in material science, nanotechnology and life sciences. At present, however, the overall industrial processes to produce these phosphorus compounds are unsustainable, energy-intensive, and inefficient.

To meet the growing demand for phosphorus derivatives, whilst complying with increasingly stringent environmental regulations and sustainability issues, we will advance P(III)/P(V) redox cycling and modernise the use of phosphorus by developing novel one-electron processes that minimise unnecessary redox reactions. Our interdisciplinary approach in organophosphorus chemistry exploits all facets of physical (in)organic chemistry, with a key focus on synthesis, molecular and mechanistic design, and sustainability. In our research projects, we will develop:

• (i) the controlled generation of P-radicals and their reactivity to establish novel open-shell (radical) pathways, thereby advancing P-sustainability and the eco-friendly production of benign phosphorus compounds; and
• (ii) novel redox reactions of phosphines, spent phosphine oxides, phosphoric acid and waste phosphates to enable their use as renewable feedstocks for chemicals traditionally synthesised from elemental white phosphorus (P₄), which will prevent their constant spillage in the environment.

We will implement these innovations into a broader context and develop scalable protocols, which are needed to realize sustainable phosphorus chemistry on a large scale, introducing recycling, clean, and ‘cradle-to-cradle’ technologies as ground-breaking changes in the field to ensure the continued beneficial use of phosphorus. This research project has significant relevance for the Dutch National Research Agenda on Circular economy and resource efficiency: it will enforce a paradigm shift by developing efficient redox cycling methods to convert waste phosphates directly into high-value products using novel synthetic methodologies, and hence, contribute to modernising phosphorus chemistry by setting new frontiers.

Safe and Sustainable by Design

Over 350.000 chemicals and mixtures of chemicals have been registered for production and use worldwide,  and these products and their constituents are found everywhere, including in waste products, soils, water, air, plants, food, animals, and the human body. Furthermore, environmental wastes and pollutants often are the sources of new, sometimes even more toxic, molecules formed as transformation products. There is therefore an urgent need for the design of safer molecules and materials that permit fast and complete environmental mineralization while retaining their desired functions. 

Optimal product design should target the most favourable end-of-life state, avoiding persistence in the environment and breakdown into harmful products. We will showcase safe and environmentally benign organophosphate flame retardants with enhanced biodegradability by bringing together sustainable synthesis and design with a key focus on (eco)toxicology, environmental impact, and implementation along the value chain. Furthermore, we will also generate the environmental health and safety data of our benign and circular organophosphates, which will make them more easily marketable.

Content will be added soon

2024

The three paradigms of sustainable chemistry
In a paper in One Earth Chris presents an integrated view of a fully sustainable future chemistry by bringing together the three underlying paradigms: green chemistry, circular chemistry, and safe-and-sustainable-by-design (SSbD).

Critical Raw Materials
Together with Benjamin Sprecher and René Kleijn, Chris advocates for the smart and circular use of Critical Raw Materials in FD and C2W.

TEDxAUC
Chris gave a TEDx talk:

Modern Chemistry is Rubbish
Hannah and Chris addressed the statement Modern Chemistry is Rubbish in the Nature Portfolio.

Academic Bubble vs Societal Relevance
Chris highlighted the relevance of academic, curiosity driven reserach AND fundamental research with societal impact in this interview in C2W.

Research into Hydrogen Storage
Our research activities into circular hydrogen storage materials is featured in Folia and in this nice video.

2023

Sustainability & Circularity NOW
Chris has been named Editor-in-Chief of the new journal Sustainability & Circularity NOW, published by Thieme.

Awards for Hannah Flerlage
Hannah received a poster prize (2nd place) and won a Travel Grant at the European Meeting on Fire Retardant Polymeric Materials in Zürich.

2022

Hoe pas je safe and sustainable by design toe?
(VNCI)
Veiliger en duurzamer ontwerpen
(C2W)
Hannah and Chris highlight the importance of safe and sustainable design of chemicals in Chemie Magazine of the Royal Association of the Dutch Chemical Industry (VNCI) and Hannah also highlighted this in C2W.

Design thinking en duurzame chemie
(C2W)
Tess was interviewed by C2W on her work on Design Thinking and Sustainable Chemistry, as well as her ambitions to contribute to a more sustainable world.

Kan de waterstofkorrel ons van het gas afhelpen?
Tess and Chris showcase the use of NaBH₄ as circular hydrogen carrier in the science programme ATLAS on Dutch television.

In een lab op de UvA werken drie chemici aan een waterstofrevolutie in de scheepvaart 
(Folia)
Chris is interviewed about the work on hydrogen carriers.

2021

Chris Slootweg receives Vici grant 
Chris has been awarded an NWO Vici grant of 1.5 million euros to develop novel chemical routes for establishing circularity in phosphorus.

Hannah Flerlage wins Student Recycling Award 2021 
Hannah has won the Student Recycling Award from the Dutch industry association BRBS Recycling.

Chris Slootweg 
(Amsterdam Science Park)
Chris is portrayed in the 'Boundless Minds' series of Amsterdam Science Park:

2020

Interview with Chris Slootweg
(SYNFORM - Thieme Chemistry)
Profile of Chris in the 'Young Career Focus' series.

Stairway to Impact Award and Rabo Sustainable Innovation Award for Chris Slootweg & SusPhos
Chris receives the very first Stairway to Impact Award from Dutch funding agency NWO.

2019

Chris Slootweg in Nature Chemistry: ‘Green Chemistry is an outdated concept’.
In a recent commentary published in Nature Chemistry, Chris introduces a new concept: Circular Chemistry. In analogy to the well-known 12 principles of Green Chemistry, he presents the 12 principles of Circular Chemistry and outlines the paradigm shift that is needed in the field of chemistry in order to establish a circular economy.

Thieme chemistry journals award for Chris Slootweg
Chris is one of the recipients of the 2019 Thieme Chemistry Journals Award.

HIMS researchers collect urine at Lowlands festival
Steven, Bas and Chris showcase phosphate recovery at “A Campingflight to Lowlands Paradise”:

2018

Humboldt Research Fellowship for Chris Slootweg
Chris is recognized with a Humboldt Research Fellowship for experienced researchers.